Deep Analysis of Residue Constraints (DARC): identifying determinants of protein functional specificity

Protein functional constraints are manifest as superfamily and functional-subgroup conserved residues, and as pairwise correlations. Deep Analysis of Residue Constraints (DARC) aids the visualization of these constraints, characterizes how they correlate with each other and with structure, and estim...

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Detalles Bibliográficos
Autores principales: Tondnevis, Farzaneh, Dudenhausen, Elizabeth E., Miller, Andrew M., McKenna, Robert, Altschul, Stephen F., Bloom, Linda B., Neuwald, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997377/
https://www.ncbi.nlm.nih.gov/pubmed/32015389
http://dx.doi.org/10.1038/s41598-019-55118-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997377/
https://www.ncbi.nlm.nih.gov/pubmed/32015389
http://dx.doi.org/10.1038/s41598-019-55118-6

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