Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model

Pharmacological treatments for non-alcoholic steatohepatitis (NASH) are still unsatisfactory. Fibrosis is the most significant predictor of mortality and many anti-fibrotic agents are under evaluation. Herein, we assessed in vitro the effects of the FXR agonist obeticholic acid (OCA) and the dual FX...

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Detalles Bibliográficos
Autores principales: Anfuso, Beatrice, Tiribelli, Claudio, Adorini, Luciano, Rosso, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997404/
https://www.ncbi.nlm.nih.gov/pubmed/32015483
http://dx.doi.org/10.1038/s41598-020-58562-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997404/
https://www.ncbi.nlm.nih.gov/pubmed/32015483
http://dx.doi.org/10.1038/s41598-020-58562-x

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