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Hepatocyte apoptosis is tumor promoting in murine nonalcoholic steatohepatitis

Nonalcoholic fatty liver disease is the most common chronic liver disease and may progress to nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). The molecular determinants of this pathogenic progression, however, remain largely undefined. Since liver tumorigenesis is driven by a...

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Detalles Bibliográficos
Autores principales: Hirsova, Petra, Bohm, Friederike, Dohnalkova, Ester, Nozickova, Barbora, Heikenwalder, Mathias, Gores, Gregory J., Weber, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997423/
https://www.ncbi.nlm.nih.gov/pubmed/32015322
http://dx.doi.org/10.1038/s41419-020-2283-9