DNA sequence context as a marker of CpG methylation instability in normal and cancer tissues

DNA methylation alterations are related to multiple molecular mechanisms. The DNA context of CpG sites plays a crucial role in the maintenance and stability of methylation patterns. The quantitative relationship between DNA composition and DNA methylation has been studied in normal as well as pathol...

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Detalles Bibliográficos
Autores principales: Scala, Giovanni, Federico, Antonio, Palumbo, Domenico, Cocozza, Sergio, Greco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997448/
https://www.ncbi.nlm.nih.gov/pubmed/32015379
http://dx.doi.org/10.1038/s41598-020-58331-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997448/
https://www.ncbi.nlm.nih.gov/pubmed/32015379
http://dx.doi.org/10.1038/s41598-020-58331-w

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