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Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice

Arterial medial calcification (AMC) involves an increased small extracellular vesicle (sEV) secretion and apatite calcium precipitation in the arterial wall. The mechanisms mediating AMC remain poorly understood. In the present study, smooth muscle-specific acid ceramidase (Ac) gene knockout mice (A...

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Detalles Bibliográficos
Autores principales: Bhat, Owais M., Li, Guangbi, Yuan, Xinxu, Huang, Dandan, Gulbins, Erich, Kukreja, Rakesh C., Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997457/
https://www.ncbi.nlm.nih.gov/pubmed/32015399
http://dx.doi.org/10.1038/s41598-020-58568-5