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Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice
Arterial medial calcification (AMC) involves an increased small extracellular vesicle (sEV) secretion and apatite calcium precipitation in the arterial wall. The mechanisms mediating AMC remain poorly understood. In the present study, smooth muscle-specific acid ceramidase (Ac) gene knockout mice (A...
Autores principales: | Bhat, Owais M., Li, Guangbi, Yuan, Xinxu, Huang, Dandan, Gulbins, Erich, Kukreja, Rakesh C., Li, Pin-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997457/ https://www.ncbi.nlm.nih.gov/pubmed/32015399 http://dx.doi.org/10.1038/s41598-020-58568-5 |
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