Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases

Human lung fibroblasts (HLFs) treated with the viral mimetic polyinosine-polycytidylic acid (poly I:C) form an extracellular matrix (ECM) enriched in hyaluronan (HA) that avidly binds monocytes and lymphocytes. Mast cells are important innate immune cells in both asthma and acute respiratory infecti...

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Detalles Bibliográficos
Autores principales: Reeves, Stephen R., Barrow, Kaitlyn A., Rich, Lucille M., White, Maria P., Shubin, Nicholas J., Chan, Christina K., Kang, Inkyung, Ziegler, Steven F., Piliponsky, Adrian M., Wight, Thomas N., Debley, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997473/
https://www.ncbi.nlm.nih.gov/pubmed/32047499
http://dx.doi.org/10.3389/fimmu.2019.03159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997473/
https://www.ncbi.nlm.nih.gov/pubmed/32047499
http://dx.doi.org/10.3389/fimmu.2019.03159

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