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N-Palmitoylethanolamine Maintains Local Lipid Homeostasis to Relieve Sleep Deprivation–Induced Dry Eye Syndrome

Sleep loss is a key factor associated with dry eye. Use of a “stick over water” mouse model revealed that sleep deprivation induces accumulation of lipids, hypertrophy, and dysfunction of the lacrimal gland. These changes result in decreased tear production and dry eye clinical signs. The specific p...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Ji, Chunyan, Zheng, Ruihe, Yang, Longhe, Ren, Jie, Li, Yitian, Han, Yun, Zhou, Pan, Liu, Zuguo, Qiu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997544/
https://www.ncbi.nlm.nih.gov/pubmed/32047441
http://dx.doi.org/10.3389/fphar.2019.01622