PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion

Lymphopenic insult has been shown to precipitate the initiation of autoimmune disease in murine models such as the Non-obese diabetic mouse. Similarly, in man lymphopenia induced by mAb therapy, for instance Alemtuzumab as treatment for Multiple Sclerosis, can precipitate development of secondary au...

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Detalles Bibliográficos
Autores principales: Knipper, Johanna A., Wright, David, Cope, Andrew P., Malissen, Bernard, Zamoyska, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997546/
https://www.ncbi.nlm.nih.gov/pubmed/32047502
http://dx.doi.org/10.3389/fimmu.2020.00052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997546/
https://www.ncbi.nlm.nih.gov/pubmed/32047502
http://dx.doi.org/10.3389/fimmu.2020.00052

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