Exploration of Cell Development Pathways through High-Dimensional Single Cell Analysis in Trajectory Space

High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory space”, in which cells are defined by their distance along near...

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Detalles Bibliográficos
Autores principales: Dermadi, Denis, Bscheider, Michael, Bjegovic, Kristina, Lazarus, Nicole H., Szade, Agata, Hadeiba, Husein, Butcher, Eugene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997593/
https://www.ncbi.nlm.nih.gov/pubmed/32058956
http://dx.doi.org/10.1016/j.isci.2020.100842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997593/
https://www.ncbi.nlm.nih.gov/pubmed/32058956
http://dx.doi.org/10.1016/j.isci.2020.100842

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