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Exploration of Cell Development Pathways through High-Dimensional Single Cell Analysis in Trajectory Space
High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory space”, in which cells are defined by their distance along near...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997593/ https://www.ncbi.nlm.nih.gov/pubmed/32058956 http://dx.doi.org/10.1016/j.isci.2020.100842 |