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A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity
Primitive sterol evolution plays an important role in fossil record interpretation and offers potential therapeutic avenues for human disease resulting from nematode infections. Recognizing that C4-methyl stenol products [8(14)-lophenol] can be synthesized in bacteria while C4-methyl stanol products...
Autores principales: | Zhou, Wenxu, Fisher, Paxtyn M., Vanderloop, Boden H., Shen, Yun, Shi, Huazhong, Maldonado, Adrian J., Leaver, David J., Nes, W. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997595/ https://www.ncbi.nlm.nih.gov/pubmed/31548366 http://dx.doi.org/10.1194/jlr.RA119000317 |
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