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Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms
EZH2 is a component of the polycomb repressive complex 2 (PRC2), which is a highly conserved histone methyltransferase that methylates lysine 27 of histone 3. EZH2 mutations are associated with oncogenesis and progression of cancers. However, the relationship between the clinical outcome of patients...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997607/ https://www.ncbi.nlm.nih.gov/pubmed/32042866 http://dx.doi.org/10.1016/j.gendis.2019.05.001 |