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Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms
EZH2 is a component of the polycomb repressive complex 2 (PRC2), which is a highly conserved histone methyltransferase that methylates lysine 27 of histone 3. EZH2 mutations are associated with oncogenesis and progression of cancers. However, the relationship between the clinical outcome of patients...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Chongqing Medical University
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997607/ https://www.ncbi.nlm.nih.gov/pubmed/32042866 http://dx.doi.org/10.1016/j.gendis.2019.05.001 |