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Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle

Coronavirus (CoV) nucleocapsid (N) proteins are key for incorporating genomic RNA into progeny viral particles. In infected cells, N proteins are present at the replication-transcription complexes (RTCs), the sites of CoV RNA synthesis. It has been shown that N proteins are important for viral repli...

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Detalles Bibliográficos
Autores principales: Cong, Yingying, Ulasli, Mustafa, Schepers, Hein, Mauthe, Mario, V’kovski, Philip, Kriegenburg, Franziska, Thiel, Volker, de Haan, Cornelis A. M., Reggiori, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997762/
https://www.ncbi.nlm.nih.gov/pubmed/31776274
http://dx.doi.org/10.1128/JVI.01925-19