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JAK2-negative acute monocytic leukemia with TET2 mutation in essential thrombocythemia with JAK2 mutation with literature review

Essential thrombocythemia (ET) is an indolent myeloproliferative neoplasm (MPN) with a transformation to acute myeloid leukemia in <5% of patients. A 79-year-old man with JAK2V617F-positive ET exhibited leukocytosis with an increase in monoblastic cells, leading to a diagnosis of acute monoblasti...

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Detalles Bibliográficos
Autores principales: Ogasawara, Toshie, Kawauchi, Kiyotaka, Ono, Takuya, Marshall, Shoko, Shide, Kotaro, Shimoda, Kazuya, Mori, Naoki, Sakura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997900/
https://www.ncbi.nlm.nih.gov/pubmed/32042586
http://dx.doi.org/10.1016/j.lrr.2019.100194