Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells

microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors to mature microRNAs. Requirement of subcellular...

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Detalles Bibliográficos
Autores principales: Bose, Mainak, Chatterjee, Susanta, Chakrabarty, Yogaditya, Barman, Bahnisikha, Bhattacharyya, Suvendra N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998040/
https://www.ncbi.nlm.nih.gov/pubmed/32015087
http://dx.doi.org/10.26508/lsa.201800161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998040/
https://www.ncbi.nlm.nih.gov/pubmed/32015087
http://dx.doi.org/10.26508/lsa.201800161

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