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Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study

BACKGROUND: The GABA(A)-α5 receptor antagonist S44819 is a promising candidate to enhance functional recovery after acute ischemic stroke (IS). S44819 is currently evaluated in this indication; RESTORE brain study started in Dec 2016 and was completed in March 2019. METHODS/DESIGN: The study is a 3-...

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Detalles Bibliográficos
Autores principales: Chabriat, Hugues, Bassetti, Claudio L., Marx, Ute, Picarel-Blanchot, Françoise, Sors, Aurore, Gruget, Celine, Saba, Barbara, Wattez, Marine, Audoli, Marie-Laure, Hermann, Dirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998064/
https://www.ncbi.nlm.nih.gov/pubmed/32014032
http://dx.doi.org/10.1186/s13063-020-4072-2