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Host proteome linked to HPV E7-mediated specific gene hypermethylation in cancer pathways

BACKGROUND: Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting spec...

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Detalles Bibliográficos
Autores principales: Na Rangsee, Nopphamon, Yanatatsaneejit, Pattamawadee, Pisitkun, Trairak, Somparn, Poorichaya, Jintaridth, Pornrutsami, Topanurak, Supachai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998090/
https://www.ncbi.nlm.nih.gov/pubmed/32025240
http://dx.doi.org/10.1186/s13027-020-0271-4