Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway

BACKGROUND: Mesenchymal stem cells (MSCs) are suspected to exert neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles like exosomes containing bioactive compounds. We now investigate the mechanism by which bone marrow MSCs (BMSCs)-derived exosomes harborin...

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Detalles Bibliográficos
Autores principales: Hou, Kun, Li, Guichen, Zhao, Jinchuan, Xu, Baofeng, Zhang, Yang, Yu, Jinlu, Xu, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998092/
https://www.ncbi.nlm.nih.gov/pubmed/32014002
http://dx.doi.org/10.1186/s12974-020-1725-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998092/
https://www.ncbi.nlm.nih.gov/pubmed/32014002
http://dx.doi.org/10.1186/s12974-020-1725-8

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