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Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway
BACKGROUND: Mesenchymal stem cells (MSCs) are suspected to exert neuroprotective effects in brain injury, in part through the secretion of extracellular vesicles like exosomes containing bioactive compounds. We now investigate the mechanism by which bone marrow MSCs (BMSCs)-derived exosomes harborin...
Autores principales: | Hou, Kun, Li, Guichen, Zhao, Jinchuan, Xu, Baofeng, Zhang, Yang, Yu, Jinlu, Xu, Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998092/ https://www.ncbi.nlm.nih.gov/pubmed/32014002 http://dx.doi.org/10.1186/s12974-020-1725-8 |
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