YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment

BACKGROUND: Vascular endothelial cell alignment in the direction of flow is an adaptive response that protects against aortic diseases such as atherosclerosis. The RhoGTPases are known to regulate this alignment. We have shown previously that ARHGAP18 in endothelial cells is a negative regulator of...

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Detalles Bibliográficos
Autores principales: Coleman, Paul R., Lay, Angelina J., Ting, Ka Ka, Zhao, Yang, Li, Jia, Jarrah, Sorour, Vadas, Mathew A., Gamble, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998144/
https://www.ncbi.nlm.nih.gov/pubmed/32013974
http://dx.doi.org/10.1186/s12964-020-0511-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998144/
https://www.ncbi.nlm.nih.gov/pubmed/32013974
http://dx.doi.org/10.1186/s12964-020-0511-7

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