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YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment
BACKGROUND: Vascular endothelial cell alignment in the direction of flow is an adaptive response that protects against aortic diseases such as atherosclerosis. The RhoGTPases are known to regulate this alignment. We have shown previously that ARHGAP18 in endothelial cells is a negative regulator of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998144/ https://www.ncbi.nlm.nih.gov/pubmed/32013974 http://dx.doi.org/10.1186/s12964-020-0511-7 |