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Metabolic engineering Saccharomyces cerevisiae for de novo production of the sesquiterpenoid (+)-nootkatone

BACKGROUND: (+)-Nootkatone is a highly valued sesquiterpenoid compound, exhibiting a typical grapefruit aroma and various desired biological activities for use as aromatics and pharmaceuticals. The high commercial demand of (+)-nootkatone is predominately met by chemical synthesis, which entails the...

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Detalles Bibliográficos
Autores principales: Meng, Xiangfeng, Liu, Hui, Xu, Wenqiang, Zhang, Weixin, Wang, Zheng, Liu, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998195/
https://www.ncbi.nlm.nih.gov/pubmed/32013959
http://dx.doi.org/10.1186/s12934-020-1295-6