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Rapamycin prevents retinal neovascularization by downregulation of cyclin D1 in a mouse model of oxygen-induced retinopathy

BACKGROUND: Rapamycin (RAPA) is a potent angiogenic inhibitor and the aim of this study is to identify the inhibitory effect of RAPA on retinal neovascularization (RNV) in experimental oxygen-induced retinopathy (OIR). METHODS: Forty-two 7-day-old C57BL/6 J mice were randomly divided into normoxia c...

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Detalles Bibliográficos
Autores principales: Jiang, Feng, Wang, Ying, Du, Shufang, Jin, Heng, Han, Jindong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998223/
https://www.ncbi.nlm.nih.gov/pubmed/32013948
http://dx.doi.org/10.1186/s12886-020-1325-5