Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy

BACKGROUND: Autophagy plays a crucial role in the pathological process of cardiovascular diseases. However, little is known about the pathological mechanism underlying autophagy regulation in dilated cardiomyopathy (DCM). METHODS: We explored whether up-regulating autophagy could improve cardiac fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Bo, Shi, Haiming, Zhu, Jun, Wu, Bangwei, Geshang, Quzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998347/
https://www.ncbi.nlm.nih.gov/pubmed/32019530
http://dx.doi.org/10.1186/s12872-020-01365-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998347/
https://www.ncbi.nlm.nih.gov/pubmed/32019530
http://dx.doi.org/10.1186/s12872-020-01365-9

Ejemplares similares