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Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy
BACKGROUND: Autophagy plays a crucial role in the pathological process of cardiovascular diseases. However, little is known about the pathological mechanism underlying autophagy regulation in dilated cardiomyopathy (DCM). METHODS: We explored whether up-regulating autophagy could improve cardiac fun...
Autores principales: | Jin, Bo, Shi, Haiming, Zhu, Jun, Wu, Bangwei, Geshang, Quzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998347/ https://www.ncbi.nlm.nih.gov/pubmed/32019530 http://dx.doi.org/10.1186/s12872-020-01365-9 |
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