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TGFβ1‐induced beta‐site APP‐cleaving enzyme 2 upregulation promotes tumorigenesis through the NF‐κB signalling pathway in human gliomas

Gliomas are the most common primary malignant tumours of the central nervous system, and new molecular biomarkers are urgently needed for diagnosis and targeted therapy. Here, we report that increased beta‐site APP‐cleaving enzyme 2 (BACE2) expression is associated with increases in the grade of hum...

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Detalles Bibliográficos
Autores principales: Wang, Huizhi, Chen, Zihang, Wang, Shaobo, Gao, Xiao, Qian, Mingyu, Qiu, Wei, Zhang, Zongpu, Zhang, Shouji, Qi, Yanhua, Sun, Xiaopeng, Xue, Hao, Guo, Xing, Zhao, Rongrong, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998390/
https://www.ncbi.nlm.nih.gov/pubmed/31856384
http://dx.doi.org/10.1002/1878-0261.12623