UHRF1 downmodulation enhances antitumor effects of histone deacetylase inhibitors in retinoblastoma by augmenting oxidative stress‐mediated apoptosis

Identification of new genetic pathways or molecular targets that sensitize cancer cells to chemotherapeutic drugs may improve the efficacy of current chemotherapy. Here, we report that downmodulation of UHRF1 (ubiquitin‐like with PHD and RING finger domains 1) in retinoblastoma (RB) cells increases...

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Detalles Bibliográficos
Autores principales: Kim, Jong Kyong, Kan, Guangyan, Mao, Yu, Wu, Zhixuan, Tan, Xionghong, He, Heng, Lee, Chunsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998393/
https://www.ncbi.nlm.nih.gov/pubmed/31782885
http://dx.doi.org/10.1002/1878-0261.12607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998393/
https://www.ncbi.nlm.nih.gov/pubmed/31782885
http://dx.doi.org/10.1002/1878-0261.12607

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