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Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing

BACKGROUND: Klebsiella pneumoniae frequently harbours multidrug resistance, and current diagnostics struggle to rapidly identify appropriate antibiotics to treat these bacterial infections. The MinION device can sequence native DNA and RNA in real time, providing an opportunity to compare the utilit...

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Detalles Bibliográficos
Autores principales: Pitt, Miranda E, Nguyen, Son H, Duarte, Tânia P S, Teng, Haotian, Blaskovich, Mark A T, Cooper, Matthew A, Coin, Lachlan J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998412/
https://www.ncbi.nlm.nih.gov/pubmed/32016399
http://dx.doi.org/10.1093/gigascience/giaa002