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Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing
BACKGROUND: Klebsiella pneumoniae frequently harbours multidrug resistance, and current diagnostics struggle to rapidly identify appropriate antibiotics to treat these bacterial infections. The MinION device can sequence native DNA and RNA in real time, providing an opportunity to compare the utilit...
Autores principales: | Pitt, Miranda E, Nguyen, Son H, Duarte, Tânia P S, Teng, Haotian, Blaskovich, Mark A T, Cooper, Matthew A, Coin, Lachlan J M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998412/ https://www.ncbi.nlm.nih.gov/pubmed/32016399 http://dx.doi.org/10.1093/gigascience/giaa002 |
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