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Soft sensor based on 2D‐fluorescence and process data enabling real‐time estimation of biomass in Escherichia coli cultivations

In bioprocesses, specific process responses such as the biomass cannot typically be measured directly on‐line, since analytical sampling is associated with unavoidable time delays. Accessing those responses in real‐time is essential for Quality by Design and process analytical technology concepts. S...

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Detalles Bibliográficos
Autores principales: Bayer, Benjamin, von Stosch, Moritz, Melcher, Michael, Duerkop, Mark, Striedner, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999058/
https://www.ncbi.nlm.nih.gov/pubmed/32625044
http://dx.doi.org/10.1002/elsc.201900076