Cargando…

Differences Between Human and Murine Tau at the N-terminal End

Human tauopathies, such as Alzheimer’s disease (AD), have been widely studied in transgenic mice overexpressing human tau in the brain. The longest brain isoforms of Tau in mice and humans show 89% amino acid identity; however, the expression of the isoforms of this protein in the adult brain of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernández, Félix, Merchán-Rubira, Jesús, Vallés-Saiz, Laura, Rodríguez-Matellán, Alberto, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999090/
https://www.ncbi.nlm.nih.gov/pubmed/32063841
http://dx.doi.org/10.3389/fnagi.2020.00011