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A one‐pot process for synthesis of mitomycin analogs catalyzed by laccase/lipase optimized by response surface methodology

To reach the excellent yield as well as environmental friendliness, an efficient one‐pot process for the synthesis of 2‐methyl‐3‐n‐butylaminoyl‐1,4‐benzoquinone, a mitomycin‐like compound by the domino reaction of 2‐methyl‐1,4‐hydroquinone and butylamine using laccase/lipase as co‐catalysts, has bee...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Yao, Quancai, Li, Zewen, Yang, Fengke, Wang, Fanye, Liu, Junhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999360/
https://www.ncbi.nlm.nih.gov/pubmed/32624973
http://dx.doi.org/10.1002/elsc.201900118