Mitochondrial Ca(2+) Uptake Relieves Palmitate-Induced Cytosolic Ca(2+) Overload in MIN6 Cells

Saturated fatty acids contribute to β-cell dysfunction in the onset of type 2 diabetes mellitus. Cellular responses to lipotoxicity include oxidative stress, endoplasmic reticulum (ER) stress, and blockage of autophagy. Palmitate induces ER Ca(2+) depletion followed by notable store-operated Ca(2+)...

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Detalles Bibliográficos
Autores principales: Ly, Luong Dai, Ly, Dat Da, Nguyen, Nhung Thi, Kim, Ji-Hee, Yoo, Heesuk, Chung, Jongkyeong, Lee, Myung-Shik, Cha, Seung-Kuy, Park, Kyu-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999716/
https://www.ncbi.nlm.nih.gov/pubmed/31931552
http://dx.doi.org/10.14348/molcells.2019.0223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999716/
https://www.ncbi.nlm.nih.gov/pubmed/31931552
http://dx.doi.org/10.14348/molcells.2019.0223

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