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In situ antibody phage display yields optimal inhibitors of integrin α11/β1

Integrins are transmembrane multi-conformation receptors that mediate interactions with the extracellular matrix. In cancer, integrins influence metastasis, proliferation, and survival. Collagen-binding integrin-α11/β1, a marker of aggressive tumors that is involved in stroma-tumor crosstalk, may be...

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Detalles Bibliográficos
Autores principales: Gallo, Eugenio, Kelil, Abdellali, Bayliss, Peter E., Jeganathan, Ajitha, Egorova, Olga, Ploder, Lynda, Adams, Jarret J., Giblin, Patricia, Sidhu, Sachdev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999838/
https://www.ncbi.nlm.nih.gov/pubmed/31980006
http://dx.doi.org/10.1080/19420862.2020.1717265