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Immune-related adverse events are clustered into distinct subtypes by T-cell profiling before and early after anti-PD-1 treatment

Although anti-programmed death-1 (PD-1) treatment has shown remarkable anti-tumor efficacy, immune-related adverse events (irAEs) develop with heterogeneous clinical manifestations. However, the immunological understanding of irAEs is currently limited. In the present study, we analyzed peripheral b...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Hwan, Hur, Joon Young, Cho, Jinhyun, Ku, Bo Mi, Koh, Jiae, Koh, June Young, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Park, Keunchil, Ahn, Myung-Ju, Shin, Eui-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999841/
https://www.ncbi.nlm.nih.gov/pubmed/32076579
http://dx.doi.org/10.1080/2162402X.2020.1722023