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A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis

Colorectal cancer represents the second most common cause of cancer-related death. The human A33 transmembrane glycoprotein is a validated tumor-associated antigen, expressed in 95% of primary and metastatic colorectal cancers. Using phage display technology, we generated a human monoclonal antibody...

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Detalles Bibliográficos
Autores principales: Murer, Patrizia, Plüss, Louis, Neri, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999842/
https://www.ncbi.nlm.nih.gov/pubmed/31928310
http://dx.doi.org/10.1080/19420862.2020.1714371