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Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy
Multiple system atrophy (MSA), a progressive neurodegenerative disease characterized by autonomic dysfunction and motor impairment, is caused by the self-templated misfolding of the protein α-synuclein. With no treatment currently available, we sought to characterize the spread of α-synuclein in a t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999861/ https://www.ncbi.nlm.nih.gov/pubmed/32017806 http://dx.doi.org/10.1371/journal.ppat.1008222 |