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Enrichment of miR-126 enhances the effects of endothelial progenitor cell–derived microvesicles on modulating MC3T3-E1 cell function via Erk1/2-Bcl-2 signalling pathway

Objective: To evaluate whether EPC-MVs could promote bone regeneration by directly regulating osteoblast through miR-126. The underlying mechanisms were also explored. Methods: EPCs were isolated from bone marrow mononuclear cells. EPC-MVs were collected from EPCs cultured medium. The lentivirus was...

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Detalles Bibliográficos
Autores principales: Chen, Guanghua, Li, Peng, Liu, Zhijun, Zeng, Rong, Ma, Xiaotang, Chen, Yanfang, Xu, Haijia, Li, Zhanghua, Lin, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000145/
https://www.ncbi.nlm.nih.gov/pubmed/31050590
http://dx.doi.org/10.1080/19336896.2019.1607464