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Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents

Current treatment for combatting Chagas disease, a life-threatening illness caused by the kinetoplastid protozoan parasite Trypanosoma cruzi is inadequate, and thus the discovery of new antiparasitic compounds is of prime importance. Previous studies identified the indirubins, a class of ATP kinase...

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Detalles Bibliográficos
Autores principales: Efstathiou, Antonia, Meira, Cássio Santana, Gaboriaud-Kolar, Nicolas, Bastos, Tanira Matutino, Rocha, Vinícius Pinto Costa, Vougogiannopoulou, Konstantina, Skaltsounis, Alexios-Leandros, Smirlis, Despina, Soares, Milena Botelho Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000199/
https://www.ncbi.nlm.nih.gov/pubmed/30387370
http://dx.doi.org/10.1080/21505594.2018.1532242