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Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle

Zinc is widely recognized as essential for growth and proliferation, yet the mechanisms of how zinc deficiency arrests these processes remain enigmatic. Here we induce subtle zinc perturbations and track asynchronously cycling cells throughout division using fluorescent reporters, high throughput mi...

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Detalles Bibliográficos
Autores principales: Lo, Maria N, Damon, Leah J, Wei Tay, Jian, Jia, Shang, Palmer, Amy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000218/
https://www.ncbi.nlm.nih.gov/pubmed/32014109
http://dx.doi.org/10.7554/eLife.51107