Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones

Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. Here, we combine complementary theoretical approaches to elucidate the structural and thermodynamic details of the chaper...

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Detalles Bibliográficos
Autores principales: Assenza, Salvatore, Sassi, Alberto Stefano, Kellner, Ruth, Schuler, Benjamin, De Los Rios, Paolo, Barducci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000219/
https://www.ncbi.nlm.nih.gov/pubmed/31845888
http://dx.doi.org/10.7554/eLife.48491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000219/
https://www.ncbi.nlm.nih.gov/pubmed/31845888
http://dx.doi.org/10.7554/eLife.48491

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