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Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones
Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. Here, we combine complementary theoretical approaches to elucidate the structural and thermodynamic details of the chaper...
Autores principales: | Assenza, Salvatore, Sassi, Alberto Stefano, Kellner, Ruth, Schuler, Benjamin, De Los Rios, Paolo, Barducci, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000219/ https://www.ncbi.nlm.nih.gov/pubmed/31845888 http://dx.doi.org/10.7554/eLife.48491 |
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