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MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway

BACKGROUND: Endometrial carcinoma (EC) is one of the most common gynecological malignancies among women. Maternal embryonic leucine Zipper Kinase (MELK) is upregulated in a variety of human tumors, where it contributes to malignant phenotype and correlates with a poor prognosis. However, the biologi...

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Detalles Bibliográficos
Autores principales: Xu, Qinyang, Ge, Qiulin, Zhou, Yang, Yang, Bikang, Yang, Qin, Jiang, Shuheng, Jiang, Rongzhen, Ai, Zhihong, Zhang, Zhigang, Teng, Yincheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000338/
https://www.ncbi.nlm.nih.gov/pubmed/31915116
http://dx.doi.org/10.1016/j.ebiom.2019.102609