The microenvironmental and metabolic aspects of sorafenib resistance in hepatocellular carcinoma

In most cases, sorafenib-resistant HCC cells exhibit significant mesenchymal phenotype and stemness features. In this context, tumor cells might undergo cell fate transition in response to sorafenib or other targeted drugs in the presence or absence of genetic mutations. Therefore, understanding the...

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Detalles Bibliográficos
Autores principales: Xia, Shunjie, Pan, Yu, Liang, Yuelong, Xu, Junjie, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000339/
https://www.ncbi.nlm.nih.gov/pubmed/31918403
http://dx.doi.org/10.1016/j.ebiom.2019.102610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000339/
https://www.ncbi.nlm.nih.gov/pubmed/31918403
http://dx.doi.org/10.1016/j.ebiom.2019.102610

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