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Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance

BACKGROUND: HER2 plays a critical role in tumourigenesis and is associated with poor prognosis of patients with HER2-positive breast cancers. Although anti-HER2 drugs are beneficial for treating breast cancer, de novo, or acquired resistance often develops. Epigenetic factors are increasingly target...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Borcherding, Nicholas C., Shao, Peng, Maina, Peterson K., Zhang, Weizhou, Qi, Hank H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000350/
https://www.ncbi.nlm.nih.gov/pubmed/31923801
http://dx.doi.org/10.1016/j.ebiom.2019.102612