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Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance
BACKGROUND: HER2 plays a critical role in tumourigenesis and is associated with poor prognosis of patients with HER2-positive breast cancers. Although anti-HER2 drugs are beneficial for treating breast cancer, de novo, or acquired resistance often develops. Epigenetic factors are increasingly target...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000350/ https://www.ncbi.nlm.nih.gov/pubmed/31923801 http://dx.doi.org/10.1016/j.ebiom.2019.102612 |