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Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells: A randomised, double-blind placebo-controlled feasibility trial

BACKGROUND: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury. Here, we evaluated the effect of the DPP4 inhibitor sitagli...

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Detalles Bibliográficos
Autores principales: Tewary, Shreeya, Lucas, Emma S., Fujihara, Risa, Kimani, Peter K., Polanco, Angela, Brighton, Paul J., Muter, Joanne, Fishwick, Katherine J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Lacey, Lauren, Takeda, Satoru, Brosens, Jan J., Quenby, Siobhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000352/
https://www.ncbi.nlm.nih.gov/pubmed/31928963
http://dx.doi.org/10.1016/j.ebiom.2019.102597