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Degradation and modification of cochlear gap junction proteins in the early development of age-related hearing loss
Age-related hearing loss (ARHL) is the progressive, bilateral loss of high-frequency hearing in elderly people. Mutations in GJB2, encoding the cochlear gap junction protein connexin26 (Cx26), are the most frequent cause of hereditary deafness; however, a common molecular pathology between ARHL and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000393/ https://www.ncbi.nlm.nih.gov/pubmed/31988333 http://dx.doi.org/10.1038/s12276-020-0377-1 |