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Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin

This study explores the contributions of neutrophils to chemotherapeutic resistance and berberine-regulated cancer cell sensitivity to doxorubicin (DOX). In vitro experiments, continuous DOX treatment led to the shift of HL-60 cells to N2 neutrophils and thus induced chemotherapeutic resistance. The...

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Detalles Bibliográficos
Autores principales: Zhang, Shuhui, Zhou, Lin, Zhang, Mengdi, Wang, Yuehua, Wang, Mengqi, Du, Jincheng, Gu, Wenwen, Kui, Fuguang, Li, Jiahuan, Geng, Shengnan, Du, Gangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000449/
https://www.ncbi.nlm.nih.gov/pubmed/32063859
http://dx.doi.org/10.3389/fphar.2019.01658